Застосування нанобіотехнологічних форм куркуміну
DOI:
https://doi.org/10.20998/2413-4295.2018.09.32Ключові слова:
куркумін, наночастинки, ліпосомы, емульсійні препарати, біодоступність, антиоксидант, протипухлинний засіб, протизапальний засібАнотація
В огляді розглянуто фармакологічні аспекти використання природної гідрофобної сполуки диферулоілметану – куркуміну. Показано можливість застосування курку міну для інгібування канцерогенезу при ряді пухлинних захворювань, а також як антиоксидантний та протизапальний засіб. Розглянуто механізм впливу куркуміну на ферментну систему та різні біологічні фактори.Встановлена висока фармакологічна активність як при прийомі per os, так і при ін’єкційних способах введення. Приведені дані підтверджують можливість використання куркуміну як у наноемульсіях, так і у ліпосомальній форміПосилання
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